80% of the time I just want to save the screen capture to a certain destination with a pre-configured filename.
However, it's also very useful to sometime upload straight to Imgur, just copy to clipboard or open a Save As dialog.
While there are hotkey options for capturing window/screen/selection, there aren't for alternative destinations and it wastes too much time to have to click save 80% of the time for the times I want access to others.
I guess ideal would be an alternative shortcut which opens your desired list of destinations instead of the single one you have set it to.
Or custom hotkeys for saving various permutations of window/screen/selection to Imgur/clipboard/saveas/etc.